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Dr. Lindsay A. Rosenwald: Lifetime Achievements

September 16, 2011 at 10:15 am

Dr. Lindsay A. Rosenwald operates as a founder and chairman of the group of companies known as Paramount Capital group. These companies specialize in investment banking, venture capital, asset management, and direct investing within the biotechnology and life-sciences industry.

As a Wall Street biotechnology entrepreneur, Dr. Rosenwald is also a member of the Orion Biomedical Fund, LP and Orion Biomedical Offshore Fund, LP. These investment companies  both participate in financing start-up pharmaceutical research labs. Dr. Lindsay Rosenwald and his team seek out cutting edge bio-pharma companies and provide the needed capital for their research to move forward and he is responsible for the founding and re-capitalization of dozens of public and private companies.

Dr. Lindsay Rosenwald and the Paramount Capital portfolio of companies have found success with three new chemical entities recently approved by the Food and Drug Administration (FDA). They currently have dozens of other compounds in the clinical trial stage. One of the portfolio companies, PolaRx BioPharmaceuticals, Inc., has recently received final marketing approval for its leukemia drug called arsenic trioxide. The approval came quickly, only 30 months after the initial patient was treated in a corporate clinical trial.

One of his more successful acquisitions, Cougar Biotechnology, developed an exciting drug for late stage prostate cancer called abiraterone acetate. Dr. Lindsay Rosenwald has financed or founded a long list of other cutting edge companies such as Genta, Inc, Repligen Corporation, Cypress Bioscience, Inc., Discovery Laboratories, Inc., and Avigen, Inc.

Dr. Rosenwald graduated from Pennsylvania State University majoring in Finance and Economy graduating Beta Gamma Sigma in 1977. From 1977 to 1979, Dr. Rosenwald worked as an independent management consultant for several health care businesses. Later, he entered Temple University School of Medicine and graduated in 1983. Next Dr. Rosenwald took an internship at Abington Medical Hospital, working in a private medical practice until 1986. At this time, he took a position on Wall Street serving as a financial analyst specializing in medical research investment opportunities.

Today, Dr. Lindsay Rosenwald is well known in both the world of investing and the medical research field. He is a visionary with an eye toward innovation in drug research and development. He has over 20 years of experience in these areas and focuses on creating and promoting pioneering medical technologies that will enhance and transform the horizons of today’s life sciences and biotechnology companies.

Opus Point Partners: Preparing for growth in the Life Science and Healthcare fields

September 9, 2011 at 1:45 pm

OpusPoint Partners has been teaming up with individuals, investors, corporations and researchers with a unified mission to help fledgling companies achieve their goals, by providing the world with innovative solutions that will improve both the diagnosis and treatment of diseases. This investment into research companies that need the extra cash injection can only bode well for a world awaiting the progress made by these struggling companies to reap the benefits of great medical breakthroughs.

Mr. Michael S. Weiss in conjunction with Dr. Lindsay Rosenwald founded the OpusPoint Partners in 2009 and has steadfastly reaped success after success performing above the goals which would have been predicted. In less than two years, they’ve helped in the financing of over twenty companies, applying basic principles to best practices and processes. This has produced excellent rewards in both worlds of drug researching and business financing.

OpusPoint Partners has a promising future under the guidance of these two men who are both passionate about the world of biotechnology and have jointly founded other biotech companies through the years. With a combined 40 year track record between them in the fields of biotech and life sciences investing, there is no doubt that their experience and expertise would be instrumental in changing the way that the diagnosis and subsequent medical treatment of patients is handled.

Biotech investing is expected to be taken to a new level and OpusPoint Partners and Dr. Lindsay Rosenwald have raised the standards for advising and investing in biotechnical facilities by insisting on a strong set of values which are then reinforced by strong business principles. Investors are then provided with optimal returns with minimized risk, a formula which has already been proven effective by their successes.

Overcoming age-old techniques and procedures in medicine and healthcare will require additional effort but Dr. Rosenwald believes that this can be achieved while remaining within ethical boundaries as long as there is an injection of time, money and dedication.

The temptation to ignore ethics in exchange for greater profits has to be resisted if the founding principle of OpusPoint Partners is to be maintained. This principle is built on strong business connections with both the biotechnology and investment communities, thereby establishing a strong and successful conglomeration of partners that remain committed to honesty and integrity within the world of life science and healthcare.

The key to continued achievements in this area is the practice of integrity which has been stamped by honest investing and full open disclosure. True strength comes when companies and industry leaders have established strong relationships sharing the same values that understand that integrity is an inbuilt part of every organization’s culture and not just a good business practice. The world has become more competitive and business leaders are facing temptations of using less than ethical tactics in order to provide positive outcomes from their clinical trials to force an improvement in their earnings and profits.

OpusPoint Partners has proven that it is firmly committed to its shareholders made up of investors and employees and being different by remaining fair in all of its dealings especially when it comes to the investigating, testing and manufacture of drugs.

Dr. Lindsay Rosenwald is no stranger to merging biotechnology with financial investing. On July 10, 2009, Johnson and Johnson acquired a company called Cougar Biotech Labs for approximately one billion dollars which Dr. Rosenwald had founded under the name Cougar Biotechnology Inc. This Los Angeles based company performs research on experimental cancer drugs and has captured the interest of researchers and investors with some impressive experimental drugs that show promise. The company has already achieved success with one of these drugs which has shown great results in the treatment of latter staged prostate cancer.

Dr. Rosenwald has more than 17 years of experience as a biotechnology entrepreneur on Wall Street he has actively founded and recapitalized both private and public companies that are focused on biotechnology and life sciences. His B. S. in Finance from Pennsylvania State University and M. D. from the Temple University School of Medicine was very useful in his management of the Aries Funds (1994 to 2000) and the Orion Fund (2002-2006). The Aries fund has applied more than $1 Billion on healthcare investments while the Orion Fund has dedicated itself to private biotechnology investing in projects like PIPEs.

Dr. Lindsay Rosenwald has formed close connections to the biotechnology-finance industry leaders and is currently a member of the Board of Directors at the Republican Jewish coalition. OpusPoint Partners has geared up to prepare for the advances in healthcare and life science. Additional time and money will be invested in order to be the leaders in the latest innovations that are expected to revolutionize how healthcare is delivered. Their vision is to see a world improved by their collective input into healthcare and medicine, knowing that the future of mankind is stronger and healthier.

Advanced Prostate Cancer Patients Have More Survival Options with J&J’s Abiraterone Acetate

January 12, 2011 at 8:51 pm

In March 2009, Cougar Biotechnology, INC, one of the leading portfolio companies of BioSciences owned by Dr. Lindsay Rosenwald, announced promising results from Phase 2 trials of its investigational oral drug abiraterone acetate (CB7630) at ASCO 2009 Genitourinary Cancers Symposium, that took place in Orlando, Florida. Two poster presentations demonstrated that abiraterone acetate combined with prednisone and used in patients with chemotherapy-resistant metastatic advanced prostate cancer (also referred to as castration-resistant prostate cancer or CRPC) provide a significant survival rate when compared to a placebo plus prednisone combination.

The research, COU-AA-002, was conducted by a national medical research group, the Prostate Cancer Clinical Trials Consortium, sponsored by the Department of Defense, with Dr. C. J. Ryan, and BioSciences, with Dr. Lindsay Rosenwald, as the leading investors.

In this trial, abiraterone acetate plus prednisone was administered to chemotherapy-naïve men diagnosed with metastatic advanced prostate cancer, whose disease progressed despite hormonal therapies. In his poster presentation, Dr. Charles J. Ryan presented data supporting the valuable effect of abiraterone on the disease decline. More than 70% of patients experienced a prostate specific antigen (PSA) decline and the median time to PSA progression wasn’t noticed even after 10 months of treatment.

Another clinical trial of abiraterone acetate was conducted at the University of Texas M.D. Anderson Cancer Center (MDACC). The patients with CRPC had all radiological evidence of metastatic prostate cancer with bone metastases. 48% of the patients experienced a decline in PSA levels and an improvement in overall performance status. All patients had also a decline in bone marrow and serum testosterone to below detectable levels.

According to Cougar Biotechnology, acquired by J&J in late 2009, abiraterone acetate continues to demonstrate potent evidence of anticancer activity in patients with advanced castrate-resistant prostate cancer. More research and investments, e.g. by Lindsay Rosenwald’s BioSciences, are needed to ensure abiraterone meets unmet medical needs in patients diagnosed with metastatic prostate cancer.

In 2010, Phase III trial, COU-AA-301, as well as COU-AA-302 trial demonstrated significant survival improvement in patients, who failed first-line hormonal or docetaxel-based treatment.


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